Maxpro Mups 20 is a medication that lessens the quantity of acid your stomach produces. Heartburn, Acid reflux, and issues with your food pipe are all treated with it. Maxpro Mups 20 should be taken as prescribed by your doctor.
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Although there is no known interaction with alcohol, drinking alcohol increases acidity further and worsens issues related to the digestive system. Hence, alcohol should be avoided.
Maxpro Mups 20 may be unsafe to use during pregnancy. Although there are limited studies on humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Maxpro Mups 20 is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
It is not known whether Maxpro Mups 20 alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Maxpro Mups 20 is safe to use in patients with kidney disease. No dose adjustment of Maxpro Mups 20 is recommended. However, inform your doctor if you have any kidney disease.
Maxpro Mups 20 should be used with caution in patients with severe liver disease. A dose adjustment of Maxpro Mups 20 may be needed. Please consult your doctor.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Maxpro Mups 20 is to be taken empty stomach.
Maxpro Mups 20 is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.
Esomeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs). Maxpro Mups is used to treat certain stomach and esophagus problems (such as acid reflux, and ulcers). It works by reducing the amount of acid your stomach makes.
The H+/K+ ATPase in the gastric parietal cell is inhibited by the proton pump inhibitor esomeprazole, which reduces the amount of stomach acid produced. Esomeprazole (omeprazole's S-isomer), the first proton pump inhibitor with a single optical isomer, offers better acid control than racemic proton pump inhibitors.
Adult:
Erosive Esophagitis-
Maintenance of healing of Erosive Esophagitis-
Risk reduction in NSAID-associated Gastric Ulcer-
H. pylori eradication (Esomeprazole MUPS tablet with 1000 mg Amoxicillin and 500 mg Clarithromycin)-
Zollinger-Ellison Syndrome and idiopathic hypersecretion-
Children:
Children (1-11) years:
Erosive esophagitis:
Children below the age of 1 year:
Renal Dose
Renal impairment: No dosage adjustment needed.
CYP2C19 and CYP3A4 substantially metabolize esomeprazole in the liver. Esomeprazole does not appear to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1, or 3A4 in vitro or in vivo investigations. There should be no clinically significant interactions with medicines processed by these CYP enzymes. Esomeprazole has no clinically significant interactions with phenytoin, warfarin, quinidine, clarithromycin, or amoxicillin, according to drug interaction studies.
Gastric acid secretion is inhibited by esomeprazole. As a result, Esomeprazole may interfere with the absorption of medications whose bioavailability is influenced by gastrointestinal pH. (e.g., ketoconazole, iron salts and digoxin).
Oral contraceptives, diazepam, phenytoin, or quinidine appear to have no effect on Esomeprazole's pharmacokinetic profile.
Clarithromycin in Combination Therapy: When esomeprazole, clarithromycin, and amoxicillin are given together, the plasma levels of esomeprazole and 14-hydroxy clarithromycin rise.
Esomeprazole is contraindicated in patients with known hypersensitivity to any of the formulations.
The manufacturer advises caution. It is not known if Esomeprazole or its metabolites appear in human breast milk.
Precautions & Warnings
Store in a cool & dry place below 25ºC, and protect from light. Keep out of reach of children.
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